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Recombinant ITGAL (Efalizumab Biosimilar) antibody

This Mouse Monoclonal antibody specifically detects ITGAL (Efalizumab Biosimilar) in FACS and in vivo. It exhibits reactivity toward Human.
Catalog No. ABIN7795106

Quick Overview for Recombinant ITGAL (Efalizumab Biosimilar) antibody (ABIN7795106)

Target

ITGAL (Efalizumab Biosimilar)

Antibody Type

Recombinant Antibody

Reactivity

Human

Host

  • 1
  • 1
  • 1
  • 1
  • 1
Mouse

Clonality

  • 3
  • 2
Monoclonal

Conjugate

  • 5
This ITGAL (Efalizumab Biosimilar) antibody is un-conjugated

Application

Flow Cytometry (FACS), In vivo Studies (in vivo)

Grade

Research Grade
  • Expression System

    Mammalian cells

    Purpose

    Efalizumab Biosimilar, CD11a Monoclonal Antibody

    Characteristics

    Efalizumab Biosimilar uses the same protein sequences as the therapeutic antibody efalizumab. Efalizumab is a monoclonal anti-CD11a antibody used to treat moderate to severe plaque psoriasis. Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin. Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes. As a result efalizumab decreases cell surface expression of CD11a.

    Purification

    Protein A or G affinity column

    Purity

    >95 % by reducing SDS-PAGE

    Endotoxin Level

    < 1 EU per 1 mg of the protein by the LAL method

    Immunogen

    Human CD11a
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    > 3 mg/mL

    Storage

    4 °C,-20 °C

    Storage Comment

    Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
  • Target

    ITGAL (Efalizumab Biosimilar)

    Alternative Name

    Efalizumab Biosimilar

    Target Type

    Biosimilar
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